It does allow you to know, the Type of yeast used, the grain used, etc.
Beer is made of plant mater and water cooked and fermented, being able to ID the types of plants... through genetic testing will give you what was put in.
Add in the later versions of Guinness we have and we've got a pretty good chance to recreate Guinness V1.0
As someone who doesn’t drink beer, is there any particular reason to recreate the original version? Like, surely the recipe changed from what it was to what it is for some reason, so would original Guinness even taste better than modern Guinness? Is it just a novelty thing?
Beer as a drink has substantially changed over the past few hundred years. Along with that many of the early variations/recipes just don't exist any more (some of the 'beers' that they had historically predate things like paper... and writing), so recreating older recipes is always an interest of the industry/beer historians/enthusiasts.
While actual interest would mostly be a mix of novelty and genuine interest. Guinness back in the 1860s would likely be a significantly stronger flavoured drink, among other things.
Will you see it sold on shelves? Unlikely, is it interesting, and would I buy it if it was? yes.
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